منابع مشابه
Endothelial-regenerating cells: an expanding universe.
Atherosclerosis is the most common cause for cardiovascular diseases and is based on endothelial dysfunction. A growing body of evidence suggests the contribution of bone marrow-derived endothelial progenitor cells, monocytic cells, and mature endothelial cells to vessel formation and endothelial rejuvenation. To this day, various subsets of these endothelial-regenerating cells have been identi...
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Background: Vascular endothelial growth factor-A (VEGF-A), an endothelial cell-specific mitogen produced by various cell types, plays important roles in cell differentiation and proliferation. In this study we investigated the effect of recombinant VEGF-A on differentiation of mesenchymal stem cells (MSCs) to endothelial cells (ECs). Methods: VEGF-A was expressed in E. coli BL21 (DE3) and BL21...
متن کاملInflammation-Angiogenesis Cross-Talk and Endothelial Progenitor Cells: A Crucial Axis in Regenerating Vessels
The normal cell is confined by its genetic program to a rather narrow range of morphofunctional characteristics within which it is nevertheless able to handle normal physiological demands (Kumar et al., 2011). A single cell, placed in an appropriate environment, contains, enclosed in its genome, sufficient information to generate a variety of differentiated cell types, whose spatial and tempora...
متن کاملArterial macrophages and regenerating endothelial cells express P-selectin in atherosclerosis-prone apolipoprotein E-deficient mice.
P-selectin expression has been reported in platelets, endothelial cells, and vascular smooth muscle cells in response to vascular injury. Here, we report P-selectin expression on macrophages in the arterial wall after carotid denudation injury and spontaneous atherosclerosis in atherosclerosis-prone apoE-deficient (apoE(-/-)) mice. Double-immunofluorescence staining revealed robust P-selectin e...
متن کاملCell-surface receptors of normal, regenerating, and cultured corneal epithelial and endothelial cells.
The presence of cell-surface receptors accessible to antibodies on regenerating and cultured, but not on resting or metabolically inhibited, corneal epithelial and endothelial cells was established by immunofluorescence or immunocytotoxicity. The metabolically dependent antigens (MDA) can be demonstrated in the corneal cells (membranes) even when absent from the surface of viable cells. This is...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2010
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.109.134213